How does CMT affect most people?
Generally your legs, feet, arms and fingers will mainly be affected. You may feel weakness or lack of strength, as well as aches, pains and lethargy. This is all due to your muscles working harder to keep up with you!
How do I know what type of CMT I might have?
Since 1991, more than 100 different genes causing CMT have been identified and the list continues to grow.
CMT can be divided into types and subtypes. The types are the clinical pictures of CMT (CMT type 1, 2, 4, X, etc.), usually defined by inheritance pattern and nerve conductions. Subtypes (CMT1A, 2B, 4C, X1, etc.) are given only when the genetic cause is known. Each subtype corresponds to a gene: every person with CMT2B has a mutation in the RAB7 gene and everyone with CMT4C has two mutations in the SH3TC2 gene.
It is important to realise that there are varying degrees of severity when it comes to CMT and therefore an accurate diagnosis of your particular type of CMT is important in the appropriate treatment. In some cases a simple blood test is all that is necessary. In many cases there is still no accurate way of diagnosing what CMT type you may have. Sometimes a family history may help, but a consultation with a genetic specialist may be advised to give you the best chance at establishing your type. You may, however never know.
Will CMT affect me mentally?
The clear answer to this is NO!
CMT is a peripheral neuropathy. It does not interfere in the workings of the brain and therefore does not alter the abilities of the brain in the person with CMT. You’ll have to find another excuse for forgetting where you put your car keys!